PGD (GENETIC DIAGNOSIS)

Nicosia IVF Centre


Preimplantation Genetic Diagnosis

The process of detecting any disease-causing genes or chromosomal abnormalities and identifying the healthy embryos is called preimplantation genetic diagnosis (PGD). Besides being a diagnostic procedure, PGD also makes it possible for sick children to be treated with the HLA matching stem cells from their siblings.

For a successful preimplantation genetic diagnosis (PGD), a successful in vitro fertilisation (IVF) is necessary. In order to have a good outcome from the PGD, developing sufficient number of embryos (fertilised eggs) is very important. In order to succeed, introcytoplasmic sperm injection (ICSI) or in vitro fertilisation or both methods are used.

Briefly, PGD;

  • Increases the success of an in vitro fertilisation and pregnancy rates
  • Decreases the miscarriage risk and the need for medical termination
  • Decreases multiple pregnancy rates
  • Decreases the economic and psychological burden that results from recurrent unsuccessful IVF
  • Gives the family an opportunity to choose the gender of the baby

PGD was originally developed to determine genetic diseases but later it came into use for babies of mothers with advanced maternal age, patients with recurrent implantation problems and, most importantly, to select the gender of the baby before it is placed into the mother’s womb in countries where it is legal to do so.

In our clinic, we are not fully in favour of gender selection. However, when a couple wishes to have only one child or strongly desires to select the gender of the baby, gender selection may be applied for their first baby.

Among the factors that affect the success of gender selection, the two most important ones are the laboratory and the specialist who has experience in this field. Patient’s age is a factor that affects the number of developed eggs.

As a result of fetal cell sorting, which is one of the recent developments in gender selection and early disease diagnosis, we can now look at the gender of the babies of random pregnancies and investigate the presence of any known genetic diseases.